Pulmonary embolism and hemolytic anemia in a patient with cold agglutinin disease.
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چکیده
منابع مشابه
Chronic hemolytic anemia due to a monoclonal IgG cold agglutinin with anti-Pr specificity.
Immunologic studies performed in a case of autoimmune chronic hemolytic anemia with low titer cold agglutinins (1/16) demonstrated that the cold agglutinins corresponded to monoclonal IgG with anti-Pr specificity. This antibody had a large thermal amplitude, being active at 37 degrees C. These unusual characteristics may define a distinct subset of chronic cold agglutinin disease.
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Erythrocytes obtained from patients who manifest autoimmune hemolytic anemia can be divided into at least three categories by the nature of their protein coats as determined by direct antiglobulin (Coombs) test: IgG alone, IgG and complement (C), C alone. IgG antibodies were detected by direct Coombs Test at 4#{176}Cbut not at 37#{176}Cin patients of type 3 A.H.A. Experiments at 4, 10, 15, 20, ...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1981
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.45.1306